Oliver Koeberling : rechercher sur Z-Library

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1

Cannflavins from hemp sprouts, a novel cannabinoid-free hemp food product, target microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase

Werz, Oliver, Seegers, Julia, Schaible, Anja Maria, Weinigel, Christina, Barz, Dagmar, Koeberle, Andreas, Allegrone, Gianna, Pollastro, Federica, Zampieri, Lorenzo, Grassi, Gianpaolo, Appendino, Giova

Journal:

PharmaNutrition

Année:

2014

Langue:

english

Fichier:

PDF, 815 KB

english, 2014

2

Munronia pinnata (Wall.) Theob.: Unveiling phytochemistry and dual inhibition of 5-lipoxygenase and microsomal prostaglandin E2 synthase (mPGES)-1

Napagoda, Mayuri, Gerstmeier, Jana, Koeberle, Andreas, Wesely, Sandra, Popella, Sven, Lorenz, Sybille, Scheubert, Kerstin, Böcker, Sebastian, Svatoš, Aleš, Werz, Oliver

Journal:

Journal of Ethnopharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 640 KB

english, 2014

3

Multi-target approach for natural products in inflammation

Koeberle, Andreas, Werz, Oliver

Journal:

Drug Discovery Today

Année:

2014

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2014

4

Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders

Koeberle, Andreas, Werz, Oliver

Journal:

Biochemical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 446 KB

english, 2015

5

Analgesic potential of standardized methanol stem bark extract of Ficus platyphylla in mice: Mechanisms of action

Chindo, Ben A., Schröder, Helmut, Koeberle, Andreas, Werz, Oliver, Becker, Axel

Journal:

Journal of Ethnopharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 767 KB

english, 2016

6

Defined Structure-Activity Relationships of Boswellic Acids Determine Modulation of Ca2+ Mobilization and Aggregation of Human Platelets by Boswellia serrata Extracts

Siemoneit, Ulf, Tausch, Lars, Poeckel, Daniel, Paul, Michael, Northoff, Hinnak, Koeberle, Andreas, Jauch, Johann, Werz, Oliver

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 310 KB

english, 2017

7

Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis

StÃ¼rner, Klarissa Hanja, Werz, Oliver, Koeberle, Andreas, Otto, Markus, Pless, Ole, Leypoldt, Frank, Paul, Friedemann, Heesen, Christoph

Journal:

Scientific Reports

Année:

2020

Fichier:

PDF, 3.26 MB

2020

8

Totalsynthese von Myrtucommulon A

Hans Müller, Michael Paul, David Hartmann, Volker Huch, Dagmar Blaesius, Andreas Koeberle, Oliver Werz, Johann Jauch

Journal:

Angewandte Chemie

Année:

2010

Langue:

german

Fichier:

PDF, 355 KB

german, 2010

9

A Multicomponent Carba-Betti Strategy to Alkylidene Heterodimers – Total Synthesis and Structure–Activity Relationships of Arzanol

Alberto Minassi, Lavinia Cicione, Andreas Koeberle, Julia Bauer, Stefan Laufer, Oliver Werz, Giovanni Appendino

Journal:

European Journal of Organic Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 405 KB

english, 2012

10

Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E2 synthase-1

Andreas Koeberle, Eva-Maria Haberl, Antonietta Rossi, Carlo Pergola, Friederike Dehm, Hinnak Northoff, Reinhard Troschuetz, Lidia Sautebin, Oliver Werz

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2009

11

Identification of 2-mercaptohexanoic acids as dual inhibitors of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1

Christine Greiner, Heiko Zettl, Andreas Koeberle, Carlo Pergola, Hinnak Northoff, Manfred Schubert-Zsilavecz, Oliver Werz

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 833 KB

english, 2011

12

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

Koeberle, Solveigh C, Romir, Johannes, Fischer, Stefan, Koeberle, Andreas, Schattel, Verena, Albrecht, Wolfgang, Grütter, Christian, Werz, Oliver, Rauh, Daniel, Stehle, Thilo

Journal:

Nature Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 371 KB

english, 2011

13

Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol

Andreas Koeberle, Hinnak Northoff, Oliver Werz

Journal:

Biochemical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 471 KB

english, 2009

14

Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo

Julia Bauer, Andreas Koeberle, Friederike Dehm, Federica Pollastro, Giovanni Appendino, Hinnak Northoff, Antonietta Rossi, Lidia Sautebin, Oliver Werz

Journal:

Biochemical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 373 KB

english, 2011

15

MK-886, an inhibitor of the 5-lipoxygenase-activating protein, inhibits cyclooxygenase-1 activity and suppresses platelet aggregation

Andreas Koeberle, Ulf Siemoneit, Hinnak Northoff, Bettina Hofmann, Gisbert Schneider, Oliver Werz

Journal:

European Journal of Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 713 KB

english, 2009

16

Arylpyrrolizines as Inhibitors of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) or as Dual Inhibitors of mPGES-1 and 5-Lipoxygenase (5-LOX)

Liedtke, Andy J., Keck, Peter R. W. E. F., Lehmann, Frank, Koeberle, Andreas, Werz, Oliver, Laufer, Stefan A.

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 758 KB

english, 2009

17

Green tea epigallocatechin-3-gallate inhibits microsomal prostaglandin E2 synthase-1

Andreas Koeberle, Julia Bauer, Moritz Verhoff, Marika Hoffmann, Hinnak Northoff, Oliver Werz

Journal:

Biochemical and Biophysical Research Communications

Année:

2009

Langue:

english

Fichier:

PDF, 242 KB

english, 2009

18

Improved immunogenicity of a H44/76 group B outer membrane vesicle vaccine with over-expressed genome-derived Neisserial antigen 1870

Oliver Koeberling, Jo Anne Welsch, Dan M. Granoff

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 481 KB

english, 2007

19

Immunogenicity of a meningococcal native outer membrane vesicle vaccine with attenuated endotoxin and over-expressed factor H binding protein in infant rhesus monkeys

Oliver Koeberling, Anja Seubert, George Santos, Annalisa Colaprico, Mildred Ugozzoli, John Donnelly, Dan M. Granoff

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 553 KB

english, 2011

20

Total Synthesis of Myrtucommulone A

Hans Müller, Michael Paul, David Hartmann, Volker Huch, Dagmar Blaesius, Andreas Koeberle, Oliver Werz, Johann Jauch

Journal:

Angewandte Chemie International Edition

Année:

2010

Langue:

english

Fichier:

PDF, 354 KB

english, 2010

21

Pirinixic Acid Derivatives as Novel Dual Inhibitors of Microsomal Prostaglandin E 2 Synthase-1 and 5-Lipoxygenase

Koeberle, Andreas, Zettl, Heiko, Greiner, Christine, Wurglics, Mario, Schubert-Zsilavecz, Manfred, Werz, Oliver

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 238 KB

english, 2008

22

High Serum Levels of the Interleukin-33 Receptor Soluble ST2 as a Negative Prognostic Factor in Hepatocellular Carcinoma

Bergis, Dominik, Kassis, Valentin, Ranglack, Annika, Koeberle, Verena, Piiper, Albrecht, Kronenberger, Bernd, Zeuzem, Stefan, Waidmann, Oliver, Radeke, Heinfried H

Journal:

Translational Oncology

Année:

2013

Langue:

english

Fichier:

PDF, 275 KB

english, 2013

23

A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on Generalized Modules for Membrane Antigens (GMMA)

Koeberling, Oliver, Ispasanie, Emma, Hauser, Julia, Rossi, Omar, Pluschke, Gerd, Caugant, Dominique A., Saul, Allan, MacLennan, Calman A.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2014

24

Novel and Potent Inhibitors of 5-Lipoxygenase Product Synthesis Based on the Structure of Pirinixic Acid

Werz, Oliver, Greiner, Christine, Koeberle, Andreas, Hoernig, Christina, George, Sven, Popescu, Laura, Syha, Ivonne, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 123 KB

english, 2008

25

Comparison of Colorimetric Assays with Quantitative Amino Acid Analysis for Protein Quantification of Generalized Modules for Membrane Antigens (GMMA)

Rossi, Omar, Maggiore, Luana, Necchi, Francesca, Koeberling, Oliver, MacLennan, Calman A., Saul, Allan, Gerke, Christiane

Journal:

Molecular Biotechnology

Année:

2015

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2015

26

Myxochelins Target Human 5-Lipoxygenase

Schieferdecker, Sebastian, König, Stefanie, Koeberle, Andreas, Dahse, Hans-Martin, Werz, Oliver, Nett, Markus

Journal:

Journal of Natural Products

Année:

2015

Langue:

english

Fichier:

PDF, 712 KB

english, 2015

27

Complement‐Dependent Synergistic Bactericidal Activity of Antibodies against Factor H–Binding Protein, a Sparsely Distributed Meningococcal Vaccine Antigen

Welsch, Jo Anne, Ram, Sanjay, Koeberling, Oliver, Granoff, Dan M.

Journal:

The Journal of Infectious Diseases

Année:

2008

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2008

28

Bactericidal Antibody Responses Elicited by a Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Factor H–Binding Protein and Genetically Attenuated Endotoxin

Koeberling, Oliver, Seubert, Anja, Granoff, Dan M.

Journal:

The Journal of Infectious Diseases

Année:

2008

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2008

29

Protective Antibody Responses Elicited by a Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Genome‐Derived Neisserial Antigen 1870

Hou, Victor C., Koeberling, Oliver, Welsch, Jo Anne, Granoff, Dan M.

Journal:

The Journal of Infectious Diseases

Année:

2005

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2005

30

Meningococcal Factor H Binding Proteins in Epidemic Strains from Africa: Implications for Vaccine Development

Pajon, Rolando, Fergus, Andrew M., Koeberling, Oliver, Caugant, Dominique A., Granoff, Dan M., Peacock, Sharon J.

Journal:

PLoS Neglected Tropical Diseases

Année:

2011

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2011

31

Discovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol

Noha, Stefan M., Fischer, Katrin, Koeberle, Andreas, Garscha, Ulrike, Werz, Oliver, Schuster, Daniela

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2015

32

Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors

De Lucia, Daniela, Lucio, Oscar Méndez, Musio, Biagia, Bender, Andreas, Listing, Monika, Dennhardt, Sophie, Koeberle, Andreas, Garscha, Ulrike, Rizzo, Roberta, Manfredini, Stefano, Werz, Oliver, Ley,

Journal:

European Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2015

33

Pharmacological targeting of membrane rigidity: implications on cancer cell migration and invasion

Braig, Simone, Sebastian Schmidt, B U, Stoiber, Katharina, Händel, Chris, Möhn, Till, Werz, Oliver, Müller, Rolf, Zahler, Stefan, Koeberle, Andreas, Käs, Josef A, Vollmar, Angelika M

Journal:

New Journal of Physics

Année:

2015

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2015

34

Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study

Kim, Minju, Lee, Sunhoe, Park, Eun Beul, Kim, Kwang Jong, Lee, Hwi Ho, Shin, Ji-Sun, Fischer, Katrin, Koeberle, Andreas, Werz, Oliver, Lee, Kyung-Tae, Lee, Jae Yeol

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 575 KB

english, 2015

35

Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? The Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors

Iranshahi, Mehrdad, Chini, Maria Giovanna, Masullo, Milena, Sahebkar, Amirhossein, Javidnia, Azita, Chitsazian Yazdi, Mahsa, Pergola, Carlo, Koeberle, Andreas, Werz, Oliver, Pizza, Cosimo, Terracciano

Journal:

Journal of Natural Products

Année:

2015

Langue:

english

Fichier:

PDF, 7.44 MB

english, 2015

36

2,3-Dihydrobenzofuran privileged structures as new bioinspired lead compounds for the design of mPGES-1 inhibitors

Micco, Simone Di, Spatafora, Carmela, Cardullo, Nunzio, Riccio, Raffaele, Fischer, Katrin, Pergola, Carlo, Koeberle, Andreas, Werz, Oliver, Chalal, Malik, Vervandier-Fasseur, Dominique, Tringali, Corr

Journal:

Bioorganic & Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 903 KB

english, 2016

37

Design and Development of Microsomal Prostaglandin E2 Synthase-1 Inhibitors: Challenges and Future Directions

Koeberle, Andreas, Laufer, Stefan A., Werz, Oliver

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2016

38

Predictive Bioinformatic Assignment of Methyl-Bearing Stereocenters, Total Synthesis, and an Additional Molecular Target of Ajudazol B

Essig, Sebastian, Schmalzbauer, Björn, Bretzke, Sebastian, Scherer, Olga, Koeberle, Andreas, Werz, Oliver, Müller, Rolf, Menche, Dirk

Journal:

Journal of Organic Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 4.04 MB

english, 2016

39

Targeted Therapy for Patients with BRAF-Mutant Lung Cancer Results from the European EURAF Cohort

Gautschi, Oliver, Milia, Julie, Cabarrou, Bastien, Bluthgen, Marie-Virginia, Besse, Benjamin, Smit, Egbert F, Wolf, Juergen, Peters, Solange, Früh, Martin, Koeberle, Dieter, Oulkhouir, Youssouf, Schul

Journal:

Journal of Thoracic Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 743 KB

english, 2015

40

Corrigendum to “Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors” [Eur. J. Med. Chem. 101 (2015) 573–583]

de Lucia, Daniela, Lucio, Oscar Méndez, Musio, Biagia, Bender, Andreas, Listing, Monika, Dennhardt, Sophie, Koeberle, Andreas, Garscha, Ulrike, Rizzo, Roberta, Manfredini, Stefano, Werz, Oliver, Ley,

Journal:

European Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 496 KB

english, 2015

41

α-Tocopherol long-chain metabolite α-13’-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages

Wallert, Maria, Schmölz, Lisa, Koeberle, Andreas, Krauth, Verena, Glei, Michael, Galli, Francesco, Werz, Oliver, Birringer, Marc, Lorkowski, Stefan

Journal:

Molecular Nutrition & Food Research

Année:

2015

Langue:

english

Fichier:

PDF, 599 KB

english, 2015

42

In vivo and in vitro biological evaluation of the anti-inflammatory and analgesic response of carnosol and carnosic acid and in silico analysis of their target interactions

Maione, Francesco, Cantone, Vincenza, Pace, Simona, Chini, Maria Giovanna, Bisio, Angela, Romussi, Giovanni, Pieretti, Stefano, Werz, Oliver, Koeberle, Andreas, Mascolo, Nicola, Bifulco, Giuseppe

Journal:

British Journal of Pharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2016

43

Synthesis, structure determination, and biological evaluation of phenylsulfonyl hydrazide derivatives as potential anti-inflammatory agents

Park, Eun Beul, Kim, Kwang Jong, Jeong, Hui Rak, Lee, Jae Kyun, Kim, Hyoung Ja, Lee, Hwi Ho, Lim, Ji Woong, Shin, Ji-Sun, Koeberle, Andreas, Werz, Oliver, Lee, Kyung-Tae, Lee, Jae Yeol

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 545 KB

english, 2016

44

The Bibenzyl Canniprene Inhibits the Production of Pro-Inflammatory Eicosanoids and Selectively Accumulates in Some Cannabis sativa Strains

Allegrone, Gianna, Pollastro, Federica, Magagnini, Gianmaria, Taglialatela-Scafati, Orazio, Seegers, Julia, Koeberle, Andreas, Werz, Oliver, Appendino, Giovanni

Journal:

Journal of Natural Products

Année:

2017

Langue:

english

Fichier:

PDF, 491 KB

english, 2017

45

Garcinia kola – African ethno medication with anti-atherosclerotic effects?

Wallert, Maria, Heise, Julia, Chih Chen, Yung, Kluge, Stefan, Schmölz, Lisa, Schubert, Martin, Kate Searle, Amy, Koeberle, Andreas, Galli, Francesco, Werz, Oliver, Birringer, Marc, Lorkowski, Stefan,

Journal:

Free Radical Biology and Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 56 KB

english, 2017

46

Vitamin A regulates Akt signaling through the phospholipid fatty acid composition

Pein, Helmut, Koeberle, Solveigh C., Voelkel, Maria, Schneider, Freya, Rossi, Antonietta, Thürmer, Maria, Loeser, Konstantin, Sautebin, Lidia, Morrison, Helen, Werz, Oliver, Koeberle, Andreas

Journal:

The FASEB Journal

Année:

2017

Langue:

english

Fichier:

PDF, 2.34 MB

english, 2017

47

Structure-Function Relationship Studies in vitro Reveal Distinct and Specific Effects of Long-Chain Metabolites of Vitamin E

Schmölz, Lisa, Wallert, Maria, Rozzino, Nicolò, Cignarella, Andrea, Galli, Francesco, Glei, Michael, Werz, Oliver, Koeberle, Andreas, Birringer, Marc, Lorkowski, Stefan

Journal:

Molecular Nutrition & Food Research

Année:

2017

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2017

48

Discovery of new potent molecular entities able to inhibit mPGES-1

Di Micco, Simone, Terracciano, Stefania, Cantone, Vincenza, Fischer, Katrin, Koeberle, Andreas, Foglia, Antonio, Riccio, Raffaele, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2017

49

Targeting de novo lipogenesis as a novel approach in anti-cancer therapy

Stoiber, Katharina, Nagło, Olga, Pernpeintner, Carla, Zhang, Siwei, Koeberle, Andreas, Ulrich, Melanie, Werz, Oliver, Müller, Rolf, Zahler, Stefan, Lohmüller, Theobald, Feldmann, Jochen, Braig, Simone

Journal:

British Journal of Cancer

Année:

2017

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2017

50

Acetyl-CoA carboxylase 1 regulates endothelial cell migration by shifting the phospholipid composition

Glatzel, Daniel K., Koeberle, Andreas, Pein, Helmut, Loeser, Konstantin, Stark, Anna, Keksel, Nelli, Werz, Oliver, Mueller, Rolf, Bischoff, Iris, Fuerst, Robert

Journal:

The Journal of Lipid Research

Année:

2017

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2017